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April 2018

reliable systemic absorption Intravenous infusion Used in controlled pharmacokinetic characterization studies Intraperitoneal injection Common in rodent research protocols for systemic delivery Intranasal administration Investigated for GHRH analogs in sleep research applications Subcutaneous administration represents the most common research route due to ease of delivery, reproducible absorption kinetics, and sustained peptide exposure suitable for growth hormone secretion studies

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Human safety data for injectable, oral, or high-dose systemic GHK-Cu is essentially absent this route is unapproved and not supported by controlled trials

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